Engineering the Next Generation of Biomaterials for Regenerative Medicine, Drug Delivery and Disease Modeling
Engineering the Next Generation of Biomaterials for Regenerative Medicine, Drug Delivery and Disease Modeling
Gaharwar Lab - Where Science Shapes Innovation
Engineering the Future of Health Using the Biomaterials Toolkit
The Gaharwar Laboratory develops engineered biomaterials to control cellular behavior and therapeutic delivery. We design injectable and granular systems—such as hydrogel microparticles and shape-memory scaffolds—for minimally invasive tissue regeneration. Using advanced 3D extrusion and DLP bioprinters, we create functional tissues with precise architecture, advancing regenerative medicine, disease modeling, cancer bioengineering, and therapy.
Evolving Ideas — Where Science Meets Application
Ionic Medicine
Harnessing the power of bioactive ions to heal, regenerate, and deliver precision therapies.
Rejuvinating joints
Delivering transcription factors to reprogram cells and reverse osteoarthritic degeneration.
Stopping Bleeds
Developing expandable bandage that conforms to irregular wounds and rapidly stops bleeding.
Healthy Aging
Reprogramming mitochondria to restore cellular energy and function.
Bioprinted tissue models
Bioprinting 3D glioblastoma models to recapitulate tumor–vasculature interactions for studying invasion, resistance, and treatment response.
Nanotherapeutic Oncology
Targeting epithelial–mesenchymal transition (EMT) using anti-angiogenic and anti-metastatic nanotherapeutics to inhibit tumor progression.
Immune Engineering
Reprogramming macrophage polarization from M1 to M2 phenotype to promote tissue repair and regeneration.
Maternal Hemostasis
Developing injectable, biomaterial-based hemostats with controlled drug release to rapidly stop postpartum hemorrhage and improve maternal outcomes.
Prior Research Highlights
Vascular Engineering
Designing pro-angiogenic biomaterials to stimulate rapid and functional vascularization of engineered tissue scaffolds.
Bone Repair
Developed osteogenically active bioink for 3D printing irregular bone defects.
Electronic Skin
Engineering electronic skin with integrated sensors for real-time monitoring in soft robotics, prosthetics, and wearables.
Mitochondrial Disease
Engineering nanomaterials to restore mitochondrial function and reprogram cellular bioenergetics for treating mitochondrial disorders.
Acknowledgement
We are truly inspired and empowered by the generous support of the National Science Foundation (NSF), National Institutes of Health (NIH), U.S. Department of Defense (DOD), private foundations, and our donors. Your partnership has been the driving force behind our research, fueling innovation and enabling us to turn bold ideas into real-world solutions that advance human health.
Join us in shaping the future of healthcare
Your support can help accelerate groundbreaking discoveries in regenerative medicine, cancer bioengineering, and therapeutic technologies. At the Gaharwar Laboratory, we are developing next-generation biomaterials and patented innovations designed to transform patient care and improve lives.
Our technologies focused on cartilage regeneration (osteoarthritis), postpartum hemorrhage (women’s health), and mitochondrial reprogramming (healthy aging) are ready for the next stage, including large-animal preclinical trials. With your partnership, we can push the boundaries of science, train future innovators, and bring life-changing therapies closer to those who need them most.
We invite you to connect with us to learn more, see our progress firsthand, and explore how you can help make a lasting impact on human health.